SCHEMBL946090

SCHEMBL946090

O=C(CCCCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 0.55
PTGS2 P35354 7/20 0.55
MGLL Q99685 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
ALDH1A1 P00352 4/20 0.50
FAAH O00519 3/20 0.50
HPGD P15428 3/20 0.50
HTT P42858 2/20 0.50
MAPT P10636 2/20 0.50
HSP90AA1 P07900 1/20 0.50
TLR9 Q9NR96 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
PKM P14618 1/20 0.50
XBP1 P17861 1/20 0.50
MAPK1 P28482 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GPR35 Q9HC97 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9185109 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL57249 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL11033299 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL945656 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL18918259 0.98 PTGS1 (0.53) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL105903 0.94 PTGS1 (0.46) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL15578882 0.92 PTGS1 (0.48) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL15426046 0.91 PTGS1 (0.49) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL17193752 0.91 PTGS1 (0.49) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL12014013 0.91 PTGS1 (0.46) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020004535-A1 SENSOR CHIP FOR HIGH-SENSITIVITY DETECTION OF CELLS, ETC. 株式会社堀場製作所 2020-01-02 WO claimed
EP-2261666-B1 METHOD FOR DETECTION OF PNEUMOCOCCUS OTSUKA PHARMA CO LTD (JP) 2015-12-02 EP claimed
US-8241857-B2 Method for detection of pneumococcus OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-08-14 US claimed
CN-115826360-A Photosensitive polyimide composition, method for producing pattern, cured product, and electronic component 江苏艾森半导体材料股份有限公司 2023-03-21 CN disclosed
US-11125742-B2 Non-specific reaction inhibitor, method for inhibiting non-specific reaction, and kit LSI MEDIENCE CORPORATION (JP) 2021-09-21 US disclosed
CN-110941142-B Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2021-05-25 CN disclosed
CN-110941142-A Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2020-03-31 CN disclosed
WO-2020004535-A1 SENSOR CHIP FOR HIGH-SENSITIVITY DETECTION OF CELLS, ETC. 株式会社堀場製作所 2020-01-02 WO disclosed
CN-106104381-B Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2019-12-13 CN disclosed
US-20190285576-A1 SEMICONDUCTOR SENSOR, METHOD FOR PRODUCING THE SAME, AND COMBINED SENSOR TORAY INDUSTRIES, INC. (JP) 2019-09-19 US disclosed
EP-3531131-A1 SEMICONDUCTOR SENSOR AND MANUFACTURING METHOD FOR SAME, AND COMPOUND SENSOR Toray Industries, Inc. (JP) 2019-08-28 EP disclosed
WO-2003014392-A2 USE AND EVALUATION OF A [2+2] PHOTOADDITION IN IMMOBILIZATION OF OLIGONUCLEOTIDES ON A THREE-DIMENSIONAL HYDROGEL MATRIX AMERSHAM BIOSCIENCES AB (SE) 2003-02-20 WO disclosed
US-20020146730-A1 Hydrogel-based microarray signal amplification methods and devices therefor GE HEALTHCARE BIO-SCIENCES AB (SE) 2002-10-10 US disclosed
US-20020115740-A1 Hydrogels and hydrogel arrays made from reactive prepolymers crosslinked by [2 + 2] cycloaddition MOTOROLA, INC. 2002-08-22 US disclosed
US-6372813-B1 CROSSLINKING POLYACRYLAMIDE HYDROGEL, JOINING BIOMOLECULES ON SUPPORTS MOTOROLA 2002-04-16 US disclosed
EP-1190254-A2 ATTACHMENT OF BIOMOLECULE TO A POLYMERIC SOLID SUPPORT BY CYCLOADDITION OF A LINKER Amersham Biosciences AB (SE) 2002-03-27 EP disclosed
WO-2002012566-A2 THE USE AND EVALUATION OF A [2+2] PHOTOCYCLOADDITION IN IMMOBILIZATION OF OLIGONUCLEOTIDES ON A THREE-DIMENSIONAL HYDROGEL MATRIX MOTOROLA, INC. (US) 2002-02-14 WO disclosed
WO-2001001143-A2 ATTACHMENT OF BIOMOLECULE TO A POLYMERIC SOLID SUPPORT BY CYCLOADDITION OF A LINKER MOTOROLA INC. (US) 2001-01-04 WO disclosed
US-5807942-A ADDITION POLYMERIZABLE MONOMER UNIT IS ATTACHED TO ENZYME, ANTIBODY, ETC. AND RESULTING COMPOUND IS POLYMERIZED THROUGH DOUBLE BOND WITH ANOTHER MODIFIED ENZYME OR ANTIBODY OR WITH A MONOMER SUCH AS METHACRYLAMIDE, USED IN IMMUNOASSAY NOF CORPORATION (JP) 1998-09-15 US disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11125742-B2 Non-specific reaction inhibitor, method for inhibiting non-specific reaction, and kit KIT, SPR, SHBG PTGS1 469/4885PTGS2 692/4885MGLL 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.