Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 4/20 | 0.38 |
| ▸ | JAK1 | P23458 | 4/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276808 | 0.95 | NR3C1 (0.42) | NR3C1JAK2JAK1IRAK4TOP2A | |
| SCHEMBL4269932 | 0.94 | NPC1 (0.52) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL13608569 | 0.90 | NPC1 (0.51) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL3156903 | 0.88 | F10 (0.45) | NR3C1TOP2AF10CACNB4CACNA1A | |
| SCHEMBL3160208 | 0.88 | KDM4E (0.53) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL4279561 | 0.87 | KDM4E (0.43) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL4282234 | 0.87 | F10 (0.44) | NPC1RAB9AKDM4ENR3C1JAK2 | |
| SCHEMBL4272243 | 0.87 | TOP2A (0.41) | NPC1RAB9AKDM4ENR3C1TOP2A | |
| SCHEMBL13608572 | 0.86 | NPC1 (0.49) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL3159116 | 0.86 | F10 (0.48) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644334-A1 | ANTITHROMBOTIC ETHERS | Eli Lilly and Company (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004108677-A1 | ANTITHROMBOTIC ETHERS | ELI LILLY AND COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |