Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5726583 | 0.92 | MAPK14 (0.68) | MAPK14GCGR | |
| SCHEMBL22589275 | 0.84 | MAPK14 (0.58) | MAPK14GCGR | |
| SCHEMBL2646818 | 0.84 | MAPK14 (1.00) | MAPK14GCGR | |
| SCHEMBL3290870 | 0.84 | MAPK14 (1.00) | MAPK14GCGR | |
| SCHEMBL22589249 | 0.83 | MAPK14 (0.57) | MAPK14GCGR | |
| SCHEMBL22589403 | 0.82 | MAPK14 (0.72) | MAPK14GCGR | |
| SCHEMBL22589405 | 0.82 | MAPK14 (0.55) | MAPK14GCGR | |
| SCHEMBL5726974 | 0.81 | MAPK14 (0.78) | MAPK14 | |
| SCHEMBL22589175 | 0.81 | MAPK14 (0.54) | MAPK14GCGR | |
| SCHEMBL22589314 | 0.81 | MAPK14 (0.54) | MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278520-B1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO INC (US) | 2006-03-01 | — | — | EP | disclosed |
| EP-1278520-A4 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO INC (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-0863757-B1 | 2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2003-03-26 | — | — | EP | disclosed |
| US-6528531-B1 | Coccidiosis in poultry; | MERCK & CO., INC. | 2003-03-04 | — | — | US | disclosed |
| EP-1278520-A1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | Merck & Co., Inc. (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6432980-B1 | PREVENTION OF COCCIDIOSIS IN POULTRY | MERCK & CO., INC. | 2002-08-13 | — | — | US | disclosed |
| US-6384052-B1 | ANTIPROTOZOA AGENTS USING PYRROLEPYRIDINE DERIVATIVES | MERCK & CO., INC. | 2002-05-07 | — | — | US | disclosed |
| US-6291480-B1 | CONTROL OF COCCIDIOSIS IN POULTRY. | MERCK & CO., INC. | 2001-09-18 | — | — | US | disclosed |
| WO-2001034150-A1 | ALIPHATIC AMINE SUBSTITUTED PIPERIDYL DIARYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO., INC. (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034149-A1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO., INC. (US) | 2001-05-17 | — | — | WO | disclosed |
| US-5792778-A | TREATMENT OF CYTOKINE MEDIATED DISEASES | MERCK & CO., INC. (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1997005877-A1 | 2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | disclosed |