Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739835 | 0.84 | SLC2A1 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL5739832 | 0.84 | SLC2A1 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL5739828 | 0.84 | SLC2A1 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL5726236 | 0.81 | KCNH2 (0.46) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL5726592 | 0.78 | SLC2A1 (0.71) | KCNH2SLC2A1 | |
| SCHEMBL3248917 | 0.77 | KCNH2 (0.59) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL5725972 | 0.77 | SLC2A1 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL1147841 | 0.76 | KCNH2 (0.58) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL5739137 | 0.76 | SLC2A1 (0.62) | KCNH2SLC2A1 | |
| SCHEMBL5728453 | 0.76 | SLC2A1 (0.61) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719770-A2 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |
| EP-1320529-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-05-24 | — | — | EP | disclosed |
| US-20040053928-A1 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053928-A1 | Quinoline derivatives as antibacterials | AAAS, QDPR, QARS1 | KCNH2 1839/4885SLC2A1 3990/4885MTNR1A 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.