SCHEMBL5727291

SCHEMBL5727291

CCOC(Cc1ccc(OCCn2c(=O)sc3cc(/C(=N\OC)c4cccc(Br)c4)ccc32)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.64
PPARG P37231 16/20 0.64
PPARD Q03181 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5727293 1.00 PPARA (0.64) PPARAPPARGPPARD
SCHEMBL5727711 1.00 PPARA (0.64) PPARAPPARGPPARD
SCHEMBL5429733 0.94 PPARA (0.67) PPARAPPARGPPARD
SCHEMBL5421831 0.94 PPARA (0.67) PPARAPPARGPPARD
SCHEMBL5427997 0.94 PPARA (0.67) PPARAPPARGPPARD
SCHEMBL5892240 0.94 PPARA (0.64) PPARAPPARG
SCHEMBL5892241 0.94 PPARA (0.64) PPARAPPARG
SCHEMBL5892316 0.94 PPARA (0.64) PPARAPPARG
SCHEMBL5423193 0.92 PPARA (0.63) PPARAPPARGPPARD
SCHEMBL5727529 0.92 PPARA (0.63) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1502590-B1 Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes SERVIER LAB (FR) 2006-12-20 EP disclosed
US-7071221-B2 Heterocyclic oxime compounds LES LABORATOIRES SERVIER (FR) 2006-07-04 US disclosed
US-20050026973-A1 New heterocyclic oxime compounds LES LABORATOIRES SERVIER (FR) 2005-02-03 US disclosed
EP-1502590-A1 Heterocyclic oxime derivatives, process for their preparation and use thereof in the treatment of type II diabetes Les Laboratoires Servier (FR) 2005-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026973-A1 New heterocyclic oxime compounds CBR3, CBR1, CYB5R3 PPARA 1112/4885PPARG 785/4885PPARD 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.