Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | MARK3 | P27448 | 1/20 | 0.30 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.30 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726418 | 0.92 | BUB1 (0.34) | BUB1 | |
| SCHEMBL5725758 | 0.74 | BUB1 (0.37) | BUB1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL5873864 | 0.70 | CCNB2 (0.45) | BUB1 | |
| SCHEMBL15208125 | 0.64 | L3MBTL1 (0.36) | BUB1 | |
| SCHEMBL5414470 | 0.63 | HSP90AA1 (0.38) | BUB1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL6142331 | 0.62 | HSP90AA1 (0.37) | BUB1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL1161439 | 0.61 | L3MBTL1 (0.41) | BUB1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL28619984 | 0.61 | BCHE (0.39) | BUB1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL9982679 | 0.61 | L3MBTL1 (0.44) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL7345451 | 0.61 | STS (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339683-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2006-06-14 | — | — | EP | disclosed |