Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729626 | 0.87 | SLC6A2 (0.49) | SLC6A2SLC6A4 | |
| SCHEMBL2074800 | 0.86 | SLC6A2 (0.59) | SLC6A2SLC6A4 | |
| SCHEMBL6047909 | 0.79 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| SCHEMBL2073496 | 0.78 | SLC6A2 (0.70) | SLC6A2SLC6A4 | |
| SCHEMBL4090002 | 0.77 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| SCHEMBL4081289 | 0.77 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4082234 | 0.76 | SLC6A2 (0.98) | SLC6A2SLC6A4 | |
| SCHEMBL4084743 | 0.73 | SLC6A2 (0.78) | SLC6A2SLC6A4 | |
| SCHEMBL2073862 | 0.73 | SLC6A2 (0.58) | SLC6A2SLC6A4 | |
| SCHEMBL27668199 | 0.71 | SLC6A2 (0.62) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732887-A1 | 1-(1H-INDOL-1-YL)-3-(4-METHYLPIPERAZIN-1-YL)-1-PHENYL PROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE NOREPINEPHRINE (NE) AND THE SEROTONINE (5-HT) ACTIVITY AND THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | Wyeth (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005097744-A1 | 1-(1H-INDOL-1-YL)-3-(4-METHYLPIPERAZIN-1-YL)-1-PHENYL PROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE NOREPINEPHRINE (NE) AND THE SEROTONINE (5-HT) ACTIVITY AND THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | WYETH (US) | 2005-10-20 | — | — | WO | claimed |