Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728191 | 0.91 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL5728548 | 0.90 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| SCHEMBL3780351 | 0.90 | KCNH2 (0.48) | KCNH2SLC2A1 | |
| SCHEMBL3780360 | 0.90 | KCNH2 (0.48) | KCNH2SLC2A1 | |
| SCHEMBL5727549 | 0.89 | KCNH2 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL5738322 | 0.87 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL5726962 | 0.86 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL5737940 | 0.86 | KCNH2 (0.57) | KCNH2SLC2A1 | |
| SCHEMBL5728149 | 0.84 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL5726402 | 0.84 | KCNH2 (0.59) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719770-A2 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |
| EP-1320529-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-05-24 | — | — | EP | disclosed |
| US-20040053928-A1 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053928-A1 | Quinoline derivatives as antibacterials | AAAS, QDPR, QARS1 | KCNH2 1839/4885SLC2A1 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.