Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729506 | 0.85 | MAOB (0.40) | PPARAPPARGNR4A2RXRARXRB | |
| SCHEMBL27996354 | 0.81 | PPARA (0.50) | PPARAPPARGMEN1KMT2ALTA4H | |
| SCHEMBL10390840 | 0.81 | SSTR4 (0.52) | PPARAPPARGMEN1KMT2ANR4A2 | |
| SCHEMBL10556663 | 0.81 | SSTR4 (0.52) | MEN1KMT2ANR4A2MAOBSMN1; SMN2 | |
| SCHEMBL934363 | 0.81 | MAOB (0.49) | MEN1KMT2ARXRARXRBMAOB | |
| SCHEMBL20767121 | 0.78 | PPARA (0.49) | PPARAPPARGMEN1KMT2ALTA4H | |
| SCHEMBL9279032 | 0.78 | MRGPRX4 (0.45) | MEN1KMT2APTGER4MAOBSMN1; SMN2 | |
| SCHEMBL3177629 | 0.76 | MAOB (0.48) | PPARAPPARGMEN1KMT2ALTA4H | |
| SCHEMBL20049402 | 0.75 | LTA4H (0.48) | PPARAPPARGMEN1KMT2ALTA4H | |
| SCHEMBL1628333 | 0.74 | MEN1 (0.51) | PPARAPPARGMEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |