Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.71 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729895 | 0.99 | NPY1R (0.70) | NPY1RCRHR1RAB9AACKR3 | |
| SCHEMBL5729215 | 0.83 | NPY1R (1.00) | NPY1RRAB9A | |
| SCHEMBL5729413 | 0.82 | NPY1R (0.63) | NPY1RCRHR1 | |
| SCHEMBL5729799 | 0.82 | NPY1R (0.98) | NPY1RRAB9A | |
| SCHEMBL5729115 | 0.81 | NPY1R (0.62) | NPY1RCRHR1 | |
| SCHEMBL5730012 | 0.80 | NPY1R (0.54) | NPY1RCRHR1ACKR3 | |
| SCHEMBL5730013 | 0.80 | NPY1R (0.54) | NPY1RCRHR1ACKR3 | |
| SCHEMBL5729804 | 0.79 | NPY1R (0.52) | NPY1RCRHR1RAB9AACKR3 | |
| SCHEMBL5728776 | 0.75 | NPY1R (0.85) | NPY1RCRHR1RAB9A | |
| SCHEMBL5728795 | 0.73 | NPY1R (0.81) | NPY1RCRHR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218381-B1 | AMINO SUBSTITUTED PYRAZOLO¬1,5-a|-1,5-PYRIMIDINES AND PYRAZOLO¬1,5-a|-1,3,5-TRIAZINES | NEUROGEN CORP (US) | 2006-12-06 | — | — | EP | claimed |