Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888115 | 0.84 | F10 (0.44) | F10 | |
| SCHEMBL5729098 | 0.84 | F10 (0.61) | F10 | |
| Hydrochloric Acid SCHEMBL6895587 | 0.84 | F10 (0.43) | F10 | |
| Hydrochloric Acid SCHEMBL5729796 | 0.83 | F10 (0.61) | F10 | |
| SCHEMBL6797988 | 0.81 | TP53 (0.48) | F10 | |
| SCHEMBL8119105 | 0.79 | F10 (0.49) | F10 | |
| SCHEMBL5729234 | 0.79 | F10 (0.57) | F10 | |
| SCHEMBL5729725 | 0.79 | F10 (0.40) | F10CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL5729011 | 0.78 | F10 (0.39) | F10CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL5729372 | 0.76 | HTR6 (0.44) | F10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |