Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10971804 | 0.83 | — | — | |
| SCHEMBL27422026 | 0.83 | MEN1 (0.32) | — | |
| SCHEMBL27340494 | 0.83 | GAA (0.35) | RAB9AHSD17B10 | |
| SCHEMBL8714139 | 0.82 | KDM4E (0.31) | HSD17B10 | |
| SCHEMBL8352064 | 0.82 | KDM4E (0.31) | HSD17B10 | |
| SCHEMBL2578315 | 0.82 | KMT2A (0.33) | HSD17B10 | |
| SCHEMBL27718907 | 0.81 | FABP7 (0.36) | NPC1RAB9A | |
| SCHEMBL28756549 | 0.79 | KMT2A (0.35) | — | |
| SCHEMBL5729041 | 0.79 | — | — | |
| SCHEMBL27661703 | 0.79 | KMT2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52053877-A | — | — | None | — | — | JP | disclosed |
| CN-1934088-A | As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |
| EP-0351856-A2 | Thiazolo[5,4-b]azepine compounds | Takeda Chemical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |
| JP-S5253877-A | PROCES FOR REPARING NOVEL MORPHOLINE DERIVATIVES AND THEIR ACID ADDUCT S | SUMITOMO CHEM CO LTD | 1977-04-30 | — | — | JP | disclosed |