Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183889 | 0.74 | ALDH1A1 (0.49) | RAB9AALDH1A1EPHX1FAAHMGLL | |
| SCHEMBL28194974 | 0.73 | KMT2A (0.47) | SMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL2999385 | 0.70 | EPHX1 (0.54) | FABP7FABP5SMN1; SMN2HTTMMP9 | |
| SCHEMBL27675582 | 0.69 | TERT (0.34) | — | |
| SCHEMBL27422026 | 0.68 | MEN1 (0.32) | — | |
| SCHEMBL27340494 | 0.68 | GAA (0.35) | SMN1; SMN2LMNAMAPTRAB9AALDH1A1 | |
| SCHEMBL11591531 | 0.68 | EPHX1 (0.50) | FABP7FABP5STSHTTMMP9 | |
| SCHEMBL27861553 | 0.67 | — | — | |
| SCHEMBL27972706 | 0.67 | — | — | |
| SCHEMBL2886329 | 0.66 | ALDH1A1 (0.53) | FABP7FABP5SMN1; SMN2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160292-B | Synthesis of cyclen derivatives | GE HEALTHCARE AS | 2010-11-03 | — | — | CN | disclosed |
| CN-101160292-A | Synthesis of cyclen derivatives | GE HEALTHCARE AS (NO) | 2008-04-09 | — | — | CN | disclosed |