Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730998 | 0.76 | PPARG (0.63) | PPARGPPARAARMEN1KMT2A | |
| SCHEMBL4896309 | 0.76 | PPARG (0.49) | PPARGPPARAARMEN1KMT2A | |
| SCHEMBL4894869 | 0.76 | PPARG (0.44) | PPARGPPARAARMEN1KMT2A | |
| SCHEMBL5730615 | 0.76 | PPARG (0.49) | PPARGPPARAARMEN1KMT2A | |
| SCHEMBL5731070 | 0.76 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL5730294 | 0.75 | PPARG (0.52) | PPARGPPARAARMEN1KMT2A | |
| SCHEMBL4891675 | 0.74 | PPARG (0.41) | PPARGPPARAARMEN1KMT2A | |
| SCHEMBL5730719 | 0.73 | PPARG (0.43) | PPARGPPARAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5351329 | 0.73 | PPARG (0.43) | PPARGPPARAARMEN1KMT2A | |
| SCHEMBL4896308 | 0.70 | PPARG (0.67) | PPARGPPARAARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |