Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730294 | 0.89 | PPARG (0.52) | PPARGPPARAGAAPOLBMEN1 | |
| SCHEMBL5730615 | 0.87 | PPARG (0.49) | PPARGPPARAGAAPOLBMEN1 | |
| SCHEMBL4896309 | 0.82 | PPARG (0.49) | PPARGPPARAGAAMEN1KMT2A | |
| SCHEMBL5730719 | 0.79 | PPARG (0.43) | PPARGPPARAGAAMEN1KMT2A | |
| SCHEMBL14110264 | 0.77 | PPARG (0.89) | PPARGPPARAPOLBBRD4 | |
| SCHEMBL4893539 | 0.77 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL4894869 | 0.76 | PPARG (0.44) | PPARGPPARAGAAMEN1KMT2A | |
| SCHEMBL5730141 | 0.76 | PPARG (0.43) | PPARGPPARAGAAMEN1KMT2A | |
| SCHEMBL4893098 | 0.74 | PPARG (0.83) | PPARGPPARAPOLBBRD4 | |
| SCHEMBL5730171 | 0.74 | PPARG (0.62) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |