Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614860 | 0.97 | HTR2C (0.44) | PRKCIHTR2CMAPTMAPK1KMT2A | |
| SCHEMBL1320860 | 0.90 | HTR2C (0.43) | PRKCIHTR2CKMT2AATMKHK | |
| SCHEMBL1322258 | 0.90 | PRKCI (0.43) | PRKCIHTR2CMAPTMAPK1KMT2A | |
| SCHEMBL1322483 | 0.89 | KMT2A (0.42) | PRKCIHTR2CMAPTKMT2AATM | |
| SCHEMBL1321222 | 0.88 | HTR2C (0.43) | PRKCIHTR2CMAPTKMT2AATM | |
| SCHEMBL1322707 | 0.88 | PRKCI (0.42) | PRKCIHTR2CMAPTMAPK1KMT2A | |
| SCHEMBL1321523 | 0.88 | PRKCI (0.42) | PRKCIHTR2CMAPTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL5731071 | 0.88 | KMT2A (0.41) | PRKCIHTR2CMAPTKMT2AATM | |
| SCHEMBL1321633 | 0.87 | ALDH1A1 (0.48) | PRKCIHTR2CMAPTMAPK1KMT2A | |
| SCHEMBL1321737 | 0.86 | PRKCI (0.41) | PRKCIHTR2CMAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1619196-A1 | Substituted Pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and Pyrido[3',2':4,5]furo[3,2-d]-pyrimidines for use as inhibitors of PDA-4 and/or TNF-alpha release | Curacyte Discovery GmbH (DE) | 2006-01-25 | — | — | EP | disclosed |