Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963340 | 0.76 | HMGCR (0.46) | GAATSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL15604413 | 0.73 | GAA (0.46) | GAATSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL19647580 | 0.68 | GAA (0.41) | GAATSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10456471 | 0.68 | GAA (0.50) | GAATSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL9138775 | 0.68 | GAA (0.56) | GAATSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL14370458 | 0.66 | ALDH1A1 (0.45) | TSHRHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL17574069 | 0.66 | GAA (0.48) | GAATSHRALDH1A1 | |
| SCHEMBL29090047 | 0.66 | — | — | |
| SCHEMBL66105 | 0.66 | — | — | |
| SCHEMBL8627035 | 0.66 | ALDH1A1 (0.45) | GAATSHRHMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483271-B1 | HETEROCYCLIC AMIDE DERIVATIVES HAVING GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-22 | — | — | EP | disclosed |