Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880222 | 0.80 | BAZ2B (0.47) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL31321778 | 0.79 | BAZ2B (0.41) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL14207865 | 0.77 | CHEK1 (0.45) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL14207871 | 0.76 | CHEK1 (0.44) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL31321780 | 0.75 | BAZ2B (0.41) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL31321783 | 0.75 | BAZ2B (0.41) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL31321782 | 0.74 | BAZ2B (0.44) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL31321785 | 0.74 | BAZ2B (0.44) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL2373267 | 0.74 | CHEK1 (0.38) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL10313033 | 0.73 | BAZ2B (0.42) | CHEK1CHEK2BAZ2BHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551847-B1 | 3,4-ALKYLENEDIOXYTHIOPHENE COMPOUNDS AND POLYMERS THEREOF | AGFA GEVAERT (BE) | 2006-07-05 | — | — | EP | disclosed |
| US-7022811-B2 | 3,4-Alkylenedioxythiophene compounds and polymers thereof | AGFA-GEVAERT (BE) | 2006-04-04 | — | — | US | disclosed |
| US-20040072987-A1 | 3,4-Alkylenedioxythiophene compounds and polymers thereof | AGFA-GEVAERT (BE) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072987-A1 | 3,4-Alkylenedioxythiophene compounds and polymers thereof | CCNT1, TTI1, SULT1E1 | CHEK1 1172/4885CHEK2 1756/4885BAZ2B 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.