Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.50 |
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730171 | 0.89 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL5729379 | 0.81 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL5359236 | 0.81 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL4892195 | 0.77 | PPARG (0.82) | PPARGPPARAPPARD | |
| SCHEMBL5729663 | 0.77 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5350843 | 0.77 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL4895310 | 0.76 | PPARG (0.83) | PPARGPPARAPPARD | |
| SCHEMBL5729735 | 0.76 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5351857 | 0.75 | TP53 (0.59) | PPARGPPARA | |
| SCHEMBL5355635 | 0.75 | MAPT (0.52) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | claimed |
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |