Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.49 |
| ▸ | PPARG | P37231 | 18/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349232 | 0.94 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5358357 | 0.86 | PPARG (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5730668 | 0.76 | PPARG (0.54) | PPARAPPARGPPARD | |
| SCHEMBL5731070 | 0.75 | PPARG (0.44) | PPARAPPARG | |
| SCHEMBL5730014 | 0.75 | PPARG (0.53) | PPARAPPARG | |
| SCHEMBL6631311 | 0.75 | PPARG (0.55) | PPARAPPARGPPARD | |
| SCHEMBL6635382 | 0.75 | PPARG (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5731134 | 0.74 | PPARG (0.48) | PPARAPPARG | |
| SCHEMBL5204314 | 0.74 | KDM4E (0.54) | PPARAPPARGPPARD | |
| SCHEMBL6991602 | 0.74 | PPARG (0.59) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |