Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.58 |
| ▸ | PPARA | Q07869 | 16/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730014 | 0.89 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL6632292 | 0.88 | PPARA (0.50) | PPARGPPARAPPARD | |
| SCHEMBL5736143 | 0.87 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL5730668 | 0.85 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6631504 | 0.82 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL5349232 | 0.80 | PPARA (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5729514 | 0.80 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6633976 | 0.80 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL5350843 | 0.80 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL5346000 | 0.79 | EPHX1 (0.48) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100403-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |