Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | CTSD | P07339 | 1/20 | 0.65 |
| ▸ | CTSE | P14091 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925901 | 1.00 | REN (0.83) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5730812 | 1.00 | REN (0.83) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5729490 | 0.95 | REN (0.80) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5925910 | 0.95 | REN (0.80) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5729493 | 0.95 | REN (0.80) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5925895 | 0.95 | REN (0.83) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5729859 | 0.95 | REN (0.83) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5729858 | 0.95 | REN (0.83) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5925912 | 0.94 | REN (0.83) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5823417 | 0.94 | REN (0.83) | RENCYP3A4CTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622907-A1 | AZABICYCLONONENE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2006-02-08 | — | — | EP | claimed |
| WO-2004096803-A1 | AZABICYCLONONENE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2004-11-11 | — | — | WO | claimed |
| EP-1622907-A1 | AZABICYCLONONENE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004096803-A1 | AZABICYCLONONENE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2004-11-11 | — | — | WO | disclosed |