Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731705 | 0.89 | NPC1 (0.55) | ALDH1A1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5731269 | 0.88 | HPGD (0.51) | ALDH1A1SMN1; SMN2HPGDPKMMEN1 | |
| SCHEMBL5732788 | 0.87 | L3MBTL1 (0.56) | ALDH1A1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5730762 | 0.85 | POLB (0.44) | ALDH1A1NPC1SMN1; SMN2HTTPKM | |
| SCHEMBL5731389 | 0.83 | L3MBTL1 (0.41) | ALDH1A1NPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL5731294 | 0.82 | AR (0.39) | ALDH1A1NPC1TP53RAB9ALMNA | |
| SCHEMBL5731108 | 0.81 | TRPV1 (0.51) | ALDH1A1SMN1; SMN2LMNAHPGDMEN1 | |
| SCHEMBL5731113 | 0.81 | TRPV1 (0.51) | ALDH1A1SMN1; SMN2LMNAHPGDMEN1 | |
| SCHEMBL5730598 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2LMNAHPGDPKM | |
| SCHEMBL5731206 | 0.79 | MRGPRX4 (0.49) | TP53RAB9ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008346-B1 | NF-kB INHIBITORS CONTAINING BENZOQUINONE DERIVATIVES | DAIICHI ASUBIO PHARMA CO LTD (JP) | 2006-02-15 | — | — | EP | claimed |
| US-6703421-B1 | ADMINISTERING NF-KAPPA B INHIBITOR | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2004-03-09 | — | — | US | disclosed |
| EP-1132093-A1 | PREVENTIVES OR REMEDIES FOR MYOCARDITIS, DILATED CARDIOMYOPATHY AND CARDIAC INSUFFICIENCY CONTAINING NF-KAPPA B INHIBITORS AS THE ACTIVE INGREDIENT | SUNTORY LIMITED (JP) | 2001-09-12 | — | — | EP | disclosed |