Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 11/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614863 | 0.97 | PRKCI (0.52) | PRKCICHRM4KDM4EMAPTPRKCZ | |
| Hydrochloric Acid SCHEMBL5729967 | 0.96 | PRKCI (0.51) | PRKCICHRM4KDM4EMAPTPRKCZ | |
| SCHEMBL1322016 | 0.90 | PRKCI (0.50) | PRKCICHRM4KDM4EMAPTPRKCZ | |
| SCHEMBL1321699 | 0.90 | PRKCI (0.52) | PRKCICHRM4KDM4EMAPTCACNA2D1 | |
| SCHEMBL5732255 | 0.89 | PRKCI (0.44) | PRKCIKDM4EPRKCZKHKNPSR1 | |
| SCHEMBL1322263 | 0.88 | PRKCI (0.50) | PRKCICHRM4KDM4EMAPTPRKCZ | |
| SCHEMBL1320517 | 0.87 | PRKCI (0.49) | PRKCICHRM4KDM4EMAPTCACNA2D1 | |
| SCHEMBL2614862 | 0.87 | PRKCI (0.54) | PRKCICHRM4KDM4EMAPTPRKCZ | |
| SCHEMBL5731432 | 0.86 | PRKCI (0.49) | PRKCICHRM4KDM4EMAPTPRKCZ | |
| SCHEMBL1321209 | 0.86 | PRKCI (0.49) | PRKCICHRM4KDM4EMAPTPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1619196-A1 | Substituted Pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and Pyrido[3',2':4,5]furo[3,2-d]-pyrimidines for use as inhibitors of PDA-4 and/or TNF-alpha release | Curacyte Discovery GmbH (DE) | 2006-01-25 | — | — | EP | disclosed |