Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731430 | 0.94 | ACE (0.51) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731429 | 0.94 | ACE (0.51) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731489 | 0.94 | ACE (0.51) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925921 | 0.85 | DAPK1 (0.46) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925918 | 0.85 | DAPK1 (0.46) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731477 | 0.81 | FGFR1 (0.53) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731483 | 0.81 | FGFR1 (0.53) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731479 | 0.81 | FGFR1 (0.53) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925920 | 0.76 | PDE4A (0.47) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925939 | 0.75 | FGFR1 (0.51) | ACEPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615926-A1 | (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004094426-A1 | (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF | USTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED CESKÉ REPUBLIKY (CZ) | 2004-11-04 | — | — | WO | disclosed |