Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731429 | 1.00 | ACE (0.51) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731430 | 1.00 | ACE (0.51) | ACEPDE4APDE4BPDE4CPDE4D | |
| Dimethylformamide SCHEMBL5732103 | 0.94 | ACE (0.46) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925921 | 0.91 | DAPK1 (0.46) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925918 | 0.91 | DAPK1 (0.46) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731483 | 0.87 | FGFR1 (0.53) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731479 | 0.87 | FGFR1 (0.53) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5731477 | 0.87 | FGFR1 (0.53) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925920 | 0.81 | PDE4A (0.47) | ACEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5925939 | 0.80 | FGFR1 (0.51) | ACEPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128956-A1 | (Purin-6-yl) amino acid and production method thereof | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) | 2006-06-15 | — | — | US | disclosed |
| EP-1615926-A1 | (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004094426-A1 | (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF | USTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED CESKÉ REPUBLIKY (CZ) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128956-A1 | (Purin-6-yl) amino acid and production method thereof | PRPF3, PURB, PRPF31 | ACE 2964/4885PDE4A 1935/4885PDE4B 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.