Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732295 | 1.00 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL5732305 | 1.00 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL5732299 | 1.00 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL5732345 | 0.86 | CYP2C19 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL5732348 | 0.86 | CYP2C19 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL5732339 | 0.86 | CYP2C19 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL5732334 | 0.86 | CYP2C19 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL5731479 | 0.78 | FGFR1 (0.53) | ITGA4ITGB7PTPN1ITGB3ITGA2B | |
| SCHEMBL5731477 | 0.78 | FGFR1 (0.53) | ITGA4ITGB7PTPN1ITGB3ITGA2B | |
| SCHEMBL5731483 | 0.78 | FGFR1 (0.53) | ITGA4ITGB7PTPN1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128956-A1 | (Purin-6-yl) amino acid and production method thereof | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) | 2006-06-15 | — | — | US | disclosed |
| EP-1615926-A1 | (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004094426-A1 | (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF | USTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED CESKÉ REPUBLIKY (CZ) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128956-A1 | (Purin-6-yl) amino acid and production method thereof | PRPF3, PURB, PRPF31 | NPC1 4195/4885RAB9A 3789/4885SMN1; SMN2 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.