Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757418 | 0.72 | KDM4E (0.32) | POLBKMT2AALDH1A1GAA | |
| SCHEMBL10274793 | 0.71 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2HPGDPOLB | |
| SCHEMBL507474 | 0.70 | HPGD (0.43) | RAB9ANPC1SMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL505534 | 0.70 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2HPGDPOLB | |
| SCHEMBL5743363 | 0.67 | HTR2A (0.37) | NPSR1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL506898 | 0.65 | HPGD (0.41) | RAB9ANPC1SMN1; SMN2HPGDDRD3 | |
| SCHEMBL10277735 | 0.63 | SMN1; SMN2 (0.48) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| Hydrochloric Acid SCHEMBL506412 | 0.63 | MELK (0.40) | RAB9ANPC1SMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL507115 | 0.63 | LMNA (0.44) | RAB9ASMN1; SMN2KMT2AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL507095 | 0.62 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |