Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
| ▸ | UNG | P13051 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651588 | 1.00 | KDM4E (0.33) | KDM4EPTGS2RAB9AKCNJ1ALDH1A1 | |
| SCHEMBL4652630 | 1.00 | KDM4E (0.33) | KDM4EPTGS2RAB9AKCNJ1ALDH1A1 | |
| SCHEMBL5733701 | 0.87 | HDAC3 (0.34) | OPRM1 | |
| SCHEMBL4652473 | 0.87 | HDAC3 (0.34) | OPRM1 | |
| SCHEMBL4652632 | 0.80 | KDM4E (0.36) | KDM4EPTGS2RAB9AKCNJ1ALDH1A1 | |
| SCHEMBL2760934 | 0.80 | MEN1 (0.34) | KDM4EPTGS2ALDH1A1OPRM1HSD17B10 | |
| SCHEMBL2760935 | 0.80 | MEN1 (0.34) | KDM4EPTGS2ALDH1A1OPRM1HSD17B10 | |
| SCHEMBL4652825 | 0.78 | OPRM1 (0.33) | OPRM1 | |
| SCHEMBL14303661 | 0.76 | KDM4E (0.36) | KDM4EPTGS2RAB9AKCNJ1ALDH1A1 | |
| SCHEMBL4652845 | 0.76 | NAMPT (0.32) | KDM4EALDH1A1OPRM1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644320-A1 | INDANE DERIVATES AS MUSCARINIC RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005009941-A1 | INDANE DERIVATES AS MUSCARINIC RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-02-03 | — | — | WO | disclosed |