Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733002 | 0.65 | SLC6A9 (0.34) | FABP4FABP3SLC6A9 | |
| SCHEMBL5732880 | 0.64 | — | — | |
| SCHEMBL5732968 | 0.63 | GRM5 (0.31) | — | |
| SCHEMBL5823365 | 0.60 | KDM1A (0.32) | — | |
| SCHEMBL3638984 | 0.59 | EGFR (0.38) | FABP4FABP3SLC6A2SLC6A4 | |
| SCHEMBL1915186 | 0.58 | HDAC3 (0.44) | SLC6A2SLC6A4 | |
| SCHEMBL5733449 | 0.58 | — | — | |
| SCHEMBL3636790 | 0.58 | MAPK14 (0.41) | FABP4FABP3SLC6A2SLC6A4 | |
| SCHEMBL3639703 | 0.57 | MAPK14 (0.38) | FABP4FABP3SLC6A2SLC6A4 | |
| SCHEMBL5693114 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |