Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733059 | 0.85 | HCAR3 (0.35) | HCAR3 | |
| SCHEMBL5641626 | 0.82 | KCNH2 (0.35) | HCAR3 | |
| SCHEMBL5733664 | 0.76 | KDR (0.31) | — | |
| SCHEMBL5733237 | 0.73 | PTK2 (0.49) | HCAR3CYP1A2TSHRKMT2ATDP1 | |
| SCHEMBL1674384 | 0.72 | KMT2A (0.41) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL7003724 | 0.72 | PTGS1 (0.30) | — | |
| SCHEMBL1182536 | 0.72 | NPC1 (0.32) | PKM | |
| SCHEMBL23753409 | 0.71 | HCAR3 (0.36) | HCAR3KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL1456734 | 0.71 | MAPT (0.38) | KDM4ECYP1A2MAPTKMT2ATDP1 | |
| SCHEMBL4560278 | 0.69 | EPHX2 (0.46) | HCAR3MAPTTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070713-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | EP | disclosed |
| CN-1152029-C | Quinolonecarboxylic acid derivatives or salts thereof | ��ɽ��ѧ��ҵ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| CN-1299356-A | Quinolonecarboxylic acid derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2001-06-13 | — | — | CN | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |