Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224379 | 1.00 | HTR2A (0.34) | HTR2ACYP11B1CYP11B2CNR1ALOX5 | |
| SCHEMBL537301 | 0.88 | HTR2A (0.36) | HTR2ACNR1ALOX5CYP1A2PYCR1 | |
| SCHEMBL27647959 | 0.80 | CYP1A2 (0.37) | HTR2AALOX5CYP1A2PYCR1 | |
| SCHEMBL11017734 | 0.80 | SLC6A3 (0.35) | CYP11B1CYP11B2KMT2AMEN1 | |
| SCHEMBL16070602 | 0.79 | IGF1R (0.39) | HTR2AALOX5CYP1A2KMT2AMEN1 | |
| SCHEMBL3838209 | 0.79 | IGF1R (0.39) | HTR2AALOX5CYP1A2KMT2AMEN1 | |
| SCHEMBL11865749 | 0.79 | TSHR (0.42) | HTR2A | |
| SCHEMBL27878321 | 0.79 | HTR2A (0.39) | HTR2ACNR1ALOX5CYP1A2CYP2A6 | |
| SCHEMBL3838715 | 0.77 | HTR2A (0.38) | HTR2ACNR1ALOX5CYP1A2PYCR1 | |
| SCHEMBL2759038 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034092-A2 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | AMR TECHNOLOGY, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006034091-A2 | PROCESS FOR PRODUCTION OF CAREBASTINE | AMR TECHNOLOGY, INC. (US) | 2006-03-30 | — | — | WO | disclosed |