Styrene

Styrene

SCHEMBL5733434

C=C(CC=C(C)C(=O)O)C(=O)OCCO.C=CC(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.42
HPGD P15428 1/20 0.42
KDM4E B2RXH2 1/20 0.38
THRB P10828 3/20 0.36
TDP1 Q9NUW8 4/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
THRA P10827 1/20 0.32
APP P05067 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.31
POLB P06746 3/20 0.31
HCAR2 Q8TDS4 1/20 0.31
ATM Q13315 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
AKR1C3 P42330 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7903209 0.96 TSHR (0.46) TSHRHPGDKDM4ETHRBTDP1
Styrene SCHEMBL16752625 0.95 TSHR (0.38) TSHRHPGDKDM4ETHRBTDP1
Styrene SCHEMBL9009480 0.92 TSHR (0.40) TSHRHPGDKDM4ETDP1L3MBTL1
Styrene SCHEMBL5444349 0.91 KDM4E (0.43) TSHRHPGDKDM4ETDP1L3MBTL1
Styrene SCHEMBL6509931 0.90 TSHR (0.44) TSHRHPGDKDM4ETHRBTDP1
Styrene SCHEMBL8982567 0.89 MEN1 (0.34) TSHRHPGDKDM4ETHRBALDH1A1
Styrene SCHEMBL9144183 0.87 TSHR (0.44) TSHRKDM4ETDP1L3MBTL1ALDH1A1
Styrene SCHEMBL11629953 0.86 TSHR (0.40) TSHRTHRBALDH1A1AKR1C3
Styrene SCHEMBL6626991 0.86 TSHR (0.48) TSHRHPGDKDM4ETHRBTDP1
Styrene SCHEMBL10906592 0.86 TSHR (0.50) TSHRHPGDKDM4ETHRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060211594-A1 Composition based on nanoparticles or a nanolatex of polymers for fabric care RHODIA CHIMIE 2006-09-21 US disclosed
US-20060194711-A1 Preformulated additive for a composition for treating textile fiber articles and use of said additive as care agent PROCTER & GAMBLE COMPAMY, THE 2006-08-31 US disclosed
US-7094747-B2 Process for cleaning a surface using an aqueous composition containing a dispersed polymer RHODIA CHIMIE (FR) 2006-08-22 US disclosed
US-7071156-B2 Composition based on nanoparticles or a nanolatex of polymers for fabric care RHODIA CHIMIE (FR) 2006-07-04 US disclosed
US-20030109413-A1 Process for cleaning a surface using an aqueous composition containing a dispersed polymer PROCTER & GAMBLE COMPAY, THE 2003-06-12 US disclosed
US-20030050218-A1 Preformulated additive for a composition for treating textile fiber articles and use of said additive as care agent PROCTER & GAMBLE COMPAMY, THE 2003-03-13 US disclosed
US-20020065208-A1 Composition based on nanoparticles or a nanolatex of polymers for fabric care PROCTER & GAMBLE COMPAMY, THE 2002-05-30 US disclosed
EP-0406001-B1 Matrix plate for electrophotographic platemaking and printing plate NIPPON CATALYTIC CHEM IND (JP) 1996-05-08 EP disclosed
US-5166025-A Zinc fluorophthalocyanine and copolymer acrylate binder NIPPON SHOKUBAI CO., LTD. (JP) 1992-11-24 US disclosed
EP-0406001-A2 Matrix plate for electrophotographic platemaking and printing plate NIPPON SHOKUBAI CO., LTD. (JP) 1991-01-02 EP disclosed
US-4106421-A THERMOSETTING RESIN ROHM AND HAAS COMPANY (US) 1978-08-15 US disclosed
US-4062821-A Rheologically modified metal decorating and aqueous coating composition comprising copolymer latex and aminoplast ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed