Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 15/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5061912 | 0.90 | ALDH1A1 (0.43) | MTTPALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL5064927 | 0.88 | MTTP (0.37) | MTTP | |
| SCHEMBL5068061 | 0.87 | MTTP (0.38) | MTTP | |
| SCHEMBL5061948 | 0.87 | MTTP (0.36) | MTTPALDH1A1HPGDKMT2A | |
| SCHEMBL5065882 | 0.86 | MTTP (0.39) | MTTPALDH1A1HPGDKMT2A | |
| SCHEMBL5064942 | 0.86 | MTTP (0.36) | MTTPALDH1A1HPGDKMT2A | |
| SCHEMBL5065219 | 0.86 | MTTP (0.39) | MTTPALDH1A1HPGDKMT2A | |
| SCHEMBL5065173 | 0.84 | MTTP (0.38) | MTTP | |
| SCHEMBL5066048 | 0.84 | MTTP (0.35) | MTTP | |
| SCHEMBL14031667 | 0.84 | ALDH1A1 (0.37) | MTTPALDH1A1HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | disclosed |