Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655273 | 1.00 | CNR1 (0.48) | CNR1GAASMN1; SMN2KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL5734892 | 0.86 | CNR1 (0.48) | CNR1GAASMN1; SMN2KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL5736583 | 0.85 | CNR1 (0.45) | CNR1SMN1; SMN2NPSR1LMNAPKM | |
| Hydrochloric Acid SCHEMBL5736580 | 0.85 | CNR1 (0.45) | CNR1SMN1; SMN2NPSR1LMNAPKM | |
| SCHEMBL5734380 | 0.83 | TGM2 (0.48) | KMT2A | |
| Hydrochloric Acid SCHEMBL5735966 | 0.82 | CNR1 (0.53) | CNR1GAASMN1; SMN2KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL5735972 | 0.82 | CNR1 (0.53) | CNR1GAASMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL5733444 | 0.80 | F10 (0.57) | CNR1GAASMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL5733446 | 0.80 | F10 (0.57) | CNR1GAASMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL5735808 | 0.80 | F10 (0.57) | CNR1GAASMN1; SMN2KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |