Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.86 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.80 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733812 | 1.00 | ADORA2A (0.86) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL5736214 | 0.96 | ADORA2A (0.86) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL5736195 | 0.96 | ADORA2A (0.86) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL789234 | 0.93 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9173436 | 0.93 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL5737339 | 0.93 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9166176 | 0.93 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6938649 | 0.93 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL21710733 | 0.93 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9173411 | 0.93 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110554-B1 | MEDICINAL COMPOSITIONS FOR TREATING EYE DISEASES | YAMASA CORP (JP) | 2006-03-08 | — | — | EP | disclosed |
| US-6387889-B1 | REDUCING OCULAR TENSION | YAMASA CORPORATION (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1110554-A1 | MEDICINAL COMPOSITIONS FOR TREATING EYE DISEASES | YAMASA CORPORATION (JP) | 2001-06-27 | — | — | EP | disclosed |