Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5735853 | 0.99 | ATM (0.64) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5734553 | 0.90 | ATM (0.67) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5735647 | 0.89 | ATM (0.61) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5736359 | 0.89 | ATM (0.66) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5734594 | 0.88 | ATM (0.65) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5734767 | 0.88 | ATM (0.65) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5734184 | 0.87 | ATM (0.64) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5734158 | 0.85 | ATM (0.67) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5735158 | 0.84 | ATM (0.66) | ATMPKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5734975 | 0.84 | ATM (0.71) | ATMPKMSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |