Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735347 | 0.91 | F10 (0.53) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5734856 | 0.90 | F10 (0.52) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5734062 | 0.90 | F10 (0.61) | ATMF10 | |
| SCHEMBL5735084 | 0.90 | ATM (0.52) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5733992 | 0.90 | F10 (0.68) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5733709 | 0.90 | ATM (0.62) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5734844 | 0.90 | ATM (0.60) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5734594 | 0.90 | ATM (0.65) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5734553 | 0.90 | ATM (0.67) | ATMPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5734041 | 0.89 | PKM (0.55) | ATMPKMSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |