Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | PKLR | P30613 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134604 | 0.90 | MCOLN3 (0.83) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL3169939 | 0.83 | MCOLN3 (0.97) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL15014129 | 0.83 | PKM (0.89) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL30821997 | 0.82 | MCOLN3 (1.00) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL3814970 | 0.82 | MCOLN3 (1.00) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL932255 | 0.80 | MCOLN3 (0.59) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL13151736 | 0.80 | PKM (0.71) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL13632352 | 0.80 | POLB (0.65) | MCOLN3PKMLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL12655865 | 0.79 | MCOLN3 (0.71) | MCOLN3TSHRPKMMEN1KMT2A | |
| SCHEMBL20021982 | 0.79 | PKM (0.89) | MCOLN3TSHRPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| CN-1272107-A | Benzamidine derivatives as factor Xa inhibitors | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |