Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416042 | 0.81 | MAPT (0.50) | HSD17B10LMNACASP1GAASMN1; SMN2 | |
| SCHEMBL27118919 | 0.81 | ALDH1A1 (0.55) | LMNAGAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL5734883 | 0.77 | GAA (0.47) | HSD17B10LMNACASP1GAASMN1; SMN2 | |
| SCHEMBL11183137 | 0.76 | KMT2A (0.48) | HSD17B10LMNACASP1GAASMN1; SMN2 | |
| SCHEMBL9203846 | 0.76 | ALDH1A1 (0.39) | HSD17B10LMNAGAASMN1; SMN2MAPK1 | |
| SCHEMBL9299422 | 0.75 | ALDH1A1 (0.41) | LMNAGAASMN1; SMN2NPSR1MAPT | |
| SCHEMBL16421474 | 0.75 | ALDH1A1 (0.50) | HSD17B10CASP1GAASMN1; SMN2MAPT | |
| SCHEMBL9191286 | 0.74 | MEN1 (0.54) | HSD17B10LMNACASP1GAASMN1; SMN2 | |
| SCHEMBL28477572 | 0.73 | ALDH1A1 (0.54) | HSD17B10LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL5085232 | 0.71 | MEN1 (0.57) | HSD17B10LMNACASP1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189804-A1 | Synthetic method for the preparation of quinazolin-4-one derivative | BTG INTERNATIONAL LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
| EP-1675831-A2 | SYNTHETIC METHOD FOR THE PREPARATION OF QUINAZOLIN-4-ONE DERIVATIVES | BTG INTERNATIONAL LIMITED (GB) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005012260-A2 | SYNTHETIC METHOD FOR THE PREPARATION OF QUINAZOLIN-4-ONE DERIVATIVE | BTG INTERNATIONAL LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189804-A1 | Synthetic method for the preparation of quinazolin-4-one derivative | CYP4F3, CYP3A4, CYP4F11 | HSD17B10 2071/4885LMNA 2952/4885CASP1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.