Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831374 | 0.78 | GAA (0.37) | FAAHGAAHCAR3 | |
| SCHEMBL22952384 | 0.77 | FAAH (0.39) | FAAHCES1S1PR4S1PR1S1PR3 | |
| SCHEMBL22023892 | 0.77 | FAAH (0.36) | FAAHCES1 | |
| SCHEMBL22059374 | 0.77 | FAAH (0.39) | FAAHCES1 | |
| SCHEMBL19966809 | 0.77 | FAAH (0.39) | FAAHCES1S1PR4S1PR1S1PR3 | |
| SCHEMBL18557093 | 0.77 | FAAH (0.39) | FAAHCES1S1PR4S1PR1S1PR3 | |
| SCHEMBL21720518 | 0.76 | FAAH (0.38) | FAAHCES1S1PR4S1PR1S1PR3 | |
| SCHEMBL21884287 | 0.73 | FAAH (0.35) | FAAHCES1 | |
| SCHEMBL22660991 | 0.73 | CNR2 (0.34) | FAAHCES1CCR9 | |
| SCHEMBL22023889 | 0.73 | FAAH (0.35) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |