Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 4/20 | 0.57 |
| ▸ | F13A1 | P00488 | 3/20 | 0.57 |
| ▸ | TGM1 | P22735 | 3/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735526 | 1.00 | TGM2 (0.57) | TGM2F13A1TGM1CNR1PKM | |
| SCHEMBL5733714 | 0.84 | TGM2 (0.53) | TGM2F13A1TGM1CNR1PKM | |
| SCHEMBL5733716 | 0.84 | TGM2 (0.53) | TGM2F13A1TGM1CNR1PKM | |
| Hydrochloric Acid SCHEMBL5735057 | 0.81 | F13A1 (0.60) | TGM2F13A1TGM1CNR1PKM | |
| Hydrochloric Acid SCHEMBL5735062 | 0.81 | F13A1 (0.60) | TGM2F13A1TGM1CNR1PKM | |
| SCHEMBL5733835 | 0.79 | F10 (0.61) | CNR1PKMNPSR1MEN1KMT2A | |
| SCHEMBL5733836 | 0.79 | F10 (0.61) | CNR1PKMNPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5733822 | 0.79 | F10 (0.60) | CNR1PKMNPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5733826 | 0.79 | F10 (0.60) | CNR1PKMNPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5736586 | 0.79 | F10 (0.60) | CNR1PKMNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |