Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.68 |
| ▸ | ACE | P12821 | 3/20 | 0.65 |
| ▸ | ECE1 | P42892 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oglufanide SCHEMBL3053743 | 1.00 | ERAP2 (0.68) | ERAP2ACEECE1KDM4EMEN1 | |
| Oglufanide SCHEMBL5822555 | 1.00 | ERAP2 (0.68) | ERAP2ACEECE1KDM4EMEN1 | |
| Oglufanide SCHEMBL1898076 | 1.00 | ERAP2 (0.68) | ERAP2ACEECE1KDM4EMEN1 | |
| Oglufanide SCHEMBL5822559 | 1.00 | ERAP2 (0.68) | ERAP2ACEECE1KDM4EMEN1 | |
| Oglufanide SCHEMBL2042188 | 1.00 | ERAP2 (0.68) | ERAP2ACEECE1KDM4EMEN1 | |
| Oglufanide SCHEMBL24454642 | 1.00 | ERAP2 (0.68) | ERAP2ACEECE1KDM4EMEN1 | |
| Oglufanide SCHEMBL1898073 | 1.00 | ERAP2 (0.68) | ERAP2ACEECE1KDM4EMEN1 | |
| Oglufanide SCHEMBL27879986 | 0.99 | ERAP2 (0.67) | ERAP2ACEECE1KDM4EMEN1 | |
| SCHEMBL31483276 | 0.98 | ERAP2 (0.69) | ERAP2ACEECE1KDM4EMEN1 | |
| SCHEMBL29603192 | 0.95 | ERAP2 (0.66) | ERAP2ACEECE1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420808-A4 | TREATMENT OF TUBERCULOSIS USING IMMUNOMODULATOR COMPOUNDS | SCICLONE PHARMACEUTICALS INC (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-1420808-A1 | TREATMENT OF TUBERCULOSIS USING IMMUNOMODULATOR COMPOUNDS | Sciclone Pharmaceuticals, Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003013572-A1 | TREATMENT OF TUBERCULOSIS USING IMMUNOMODULATOR COMPOUNDS | SCICLONE PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |