Oglufanide

Oglufanide

SCHEMBL1898073

N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 1/20 0.68
ACE P12821 3/20 0.65
ECE1 P42892 6/20 0.61
KDM4E B2RXH2 1/20 0.60
MEN1 O00255 1/20 0.60
LMNA P02545 1/20 0.60
MPO P05164 1/20 0.60
MAPT P10636 1/20 0.60
TSHR P16473 1/20 0.60
BLM P54132 1/20 0.60
PMP22 Q01453 1/20 0.60
KMT2A Q03164 1/20 0.60
HIF1A Q16665 1/20 0.60
ALOX15 P16050 1/20 0.60
LTA4H P09960 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oglufanide SCHEMBL3053743 1.00 ERAP2 (0.68) ERAP2ACEECE1KDM4EMEN1
Oglufanide SCHEMBL5822555 1.00 ERAP2 (0.68) ERAP2ACEECE1KDM4EMEN1
Oglufanide SCHEMBL5735529 1.00 ERAP2 (0.68) ERAP2ACEECE1KDM4EMEN1
Oglufanide SCHEMBL1898076 1.00 ERAP2 (0.68) ERAP2ACEECE1KDM4EMEN1
Oglufanide SCHEMBL5822559 1.00 ERAP2 (0.68) ERAP2ACEECE1KDM4EMEN1
Oglufanide SCHEMBL2042188 1.00 ERAP2 (0.68) ERAP2ACEECE1KDM4EMEN1
Oglufanide SCHEMBL24454642 1.00 ERAP2 (0.68) ERAP2ACEECE1KDM4EMEN1
Oglufanide SCHEMBL27879986 0.99 ERAP2 (0.67) ERAP2ACEECE1KDM4EMEN1
SCHEMBL31483276 0.98 ERAP2 (0.69) ERAP2ACEECE1KDM4EMEN1
SCHEMBL29603192 0.95 ERAP2 (0.66) ERAP2ACEECE1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566670-A2 MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS Gilead Sciences, Inc. (US) 2025-06-11 EP claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
EP-4511379-A2 THERANOSTIC SILICON-FLUORIDE HETEROAROMATIC SYSTEMS AND METHODS THEREOF Fuzionaire Theranostics, Inc. (US) 2025-02-26 EP claimed
CN-119301134-A Silicon fluoride heteroaromatic systems for theranostics and methods therefor 富齐奥奈尔治疗诊断股份有限公司 2025-01-10 CN claimed
EP-4403221-A2 MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS Gilead Sciences, Inc. (US) 2024-07-24 EP claimed
US-11833246-B1 Rectal gel with date palm phenolics and vanillic acid King Faisal University (SA) 2023-12-05 US claimed
US-20230355813-A1 Theranostic Silicon-Fluoride Heteroaromatic Systems and Methods Thereof FUZIONAIRE DIAGNOSTICS, INC. (US) 2023-11-09 US claimed
US-11806430-B1 Rectal gel with date palm phenolics and vanillic acid King Faisal University (SA) 2023-11-07 US claimed
WO-2023205755-A2 THERANOSTIC SILICON-FLUORIDE HETEROAROMATIC SYSTEMS AND METHODS THEREOF FUZIONAIRE DIAGNOSTICS, INC. (US) 2023-10-26 WO claimed
CN-116789734-A Oligopeptide group extracted from crayfish shells, extraction method and application thereof 奇明达(北京)植物药物技术开发有限公司 2023-09-22 CN claimed
EP-2604264-B1 PHARMACEUTICAL COMPOSITION FOR TREATING VIRAL DISEASES OBSHESTVO S OGRANICHENNOJ OTVETSTVENNOSTJU CYTONIR (RU) 2014-09-24 EP claimed
EP-2767286-A1 ORAL PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY GASTROINTESTINAL DISEASES Obshestvo S Ogranichennoj Otvetstvennostju "citoNIR" (RU) 2014-08-20 EP claimed
EP-2604264-A1 PHARMACEUTICAL COMPOSITION FOR TREATING VIRAL DISEASES Obshestvo S Ogranichennoj Otvetstvennostju "citoNIR" (RU) 2013-06-19 EP claimed
WO-2012068412-A2 METHOD AND COMPOSITIONS FOR TREATMENT OF STAT3-RESPONSIVE CANCERS AND/OR RENAL CANCER SCICLONE PHARMACEUTICALS, INC. (US) 2012-05-24 WO claimed
EP-1814566-B1 TREATMENT OR PREVENTION OF HEMORRHAGIC VIRAL INFECTIONS WITH IMMUNOMODULATOR COMPOUNDS SCICLONE PHARMACEUTICALS INC (US) 2010-07-28 EP claimed
US-20030087830-A1 Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof AETERNA ZENTARIS INC. (CA) 2003-05-08 US claimed
WO-2002100421-A1 LOW MOLECULAR WEIGHT COMPONENTS OF CARTILAGE, COMPLEXES OF COPPER WITH AMINO ACIDS OR DI-PEPTIDES; PROCESSES FOR PREPARATION AND THERAPEUTIC USES THEREOF LES LABORATOIRES AETERNA INC. (CA) 2002-12-19 WO claimed
WO-1998009989-A1 THE USE OF MURAMYLPEPTIDES IN THE TREATMENT OF MYELOSUPPRESSED OR OTHERWISE IMMUNOCOMPROMISED STATES PEPTECH (UK) LIMITED (GB) 1998-03-12 WO claimed
EP-0722332-A1 COMPOUNDS FOR MEDICINAL USE PEPTECH (UK) LIMITED (GB) 1996-07-24 EP claimed
WO-1995010293-A1 COMPOUNDS FOR MEDICINAL USE PEPTECH (UK) LIMITED (GB) 1995-04-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355813-A1 Theranostic Silicon-Fluoride Heteroaromatic Systems and Methods Thereof FRS2, PAICS, FGF23 ERAP2 2337/4885ACE 2332/4885ECE1 1697/4885
US-20030087830-A1 Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof TIE1, TEK, VEGFA ERAP2 549/4885ACE 1848/4885ECE1 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.