Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371416 | 0.86 | BCL9 (0.50) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL763093 | 0.85 | BCL9 (0.54) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL6359040 | 0.83 | BCL9 (0.56) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL903436 | 0.83 | BCL9 (0.52) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL18456061 | 0.83 | HTR2A (0.53) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL31488048 | 0.82 | BCL9 (0.51) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL6348206 | 0.82 | BCL9 (0.51) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL2721373 | 0.81 | BCL9 (0.50) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL7412530 | 0.81 | BCL9 (0.45) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL7412943 | 0.81 | GAA (0.51) | HTR2ABCL9CTNNB1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449489-B2 | Indolylalkylamino-methylidenecarbamate derivatives useful as GnRH antagonists | ASTRAZENECA AB (SE) | 2008-11-11 | — | — | US | disclosed |
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |