Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385553 | 0.84 | MAPT (0.48) | EPHX2NR1H4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11363911 | 0.84 | HTT (0.53) | EPHX2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3001175 | 0.82 | SMN1; SMN2 (0.64) | EPHX2NR1H4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8868374 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2POLBHPGDKDM4E | |
| SCHEMBL28050017 | 0.79 | F2 (0.50) | EPHX2NR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL4094798 | 0.79 | ALDH1A1 (0.50) | EPHX2NR1H4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7285910 | 0.79 | KMT2A (0.44) | EPHX2NR1H4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8381562 | 0.78 | POLB (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7561667 | 0.77 | ALDH1A1 (0.49) | EPHX2NR1H4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7296941 | 0.77 | ALDH1A1 (0.52) | EPHX2NR1H4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |