Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299950 | 0.82 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL3591815 | 0.79 | DPP4 (0.41) | DPP4DPP8DPP9OPRD1GPR88 | |
| Trifluoroacetic Acid SCHEMBL5735676 | 0.79 | GRB2 (0.46) | DPP4DPP8DPP9OPRD1GPR142 | |
| SCHEMBL21299168 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL3783139 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL19699150 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL2736355 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL3136686 | 0.78 | DPP4 (0.43) | DPP4DPP8DPP9OPRD1GPR88 | |
| Hydrochloric Acid SCHEMBL7276844 | 0.77 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 | |
| Hydrochloric Acid SCHEMBL1631417 | 0.77 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933379-B1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO (JP) | 2006-03-22 | — | — | EP | disclosed |
| US-6319902-B1 | TO ACTIVATE THE CENTRAL NERVOUS SYSTEM, SUCH AS, FOR EXAMPLE, SUSTAINED ACETYLCHOLINE RELEASING ACTION, ANTI-RESERPINE ACTION AND LOCOMOTOR INCREMENT | SHIONOGI & CO., LTD. (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0933379-A1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO., LTD. (JP) | 1999-08-04 | — | — | EP | disclosed |