Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136686 | 0.89 | DPP4 (0.43) | DPP4DPP8DPP9OPRD1SCN9A | |
| SCHEMBL7299950 | 0.82 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL3783139 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL2736355 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL19699150 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9OPRD1GPR88 | |
| SCHEMBL5735685 | 0.79 | DPP4 (0.42) | DPP4DPP8DPP9OPRD1GPR88 | |
| Hydrochloric Acid SCHEMBL7385109 | 0.78 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 | |
| Hydrochloric Acid SCHEMBL27505777 | 0.78 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 | |
| Hydrochloric Acid SCHEMBL7276844 | 0.78 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 | |
| Hydrochloric Acid SCHEMBL1631417 | 0.78 | DPP4 (0.44) | DPP4DPP8DPP9OPRD1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113305-A1 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 2010-05-06 | — | — | US | disclosed |
| US-20060161007-A1 | Oxazole and thiazole combinatorial libraries | M MARTIN LENORE | 2006-07-20 | — | — | US | disclosed |
| EP-1169311-A4 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | RHODE ISLAND EDUCATION (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-1169311-A1 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000056724-A9 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | RHODE ISLAND EDUCATION (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-2000056724-A1 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113305-A1 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | OXA1L, SPOUT1, BCAT2 | DPP4 154/4885DPP8 174/4885DPP9 170/4885 |
| US-20060161007-A1 | Oxazole and thiazole combinatorial libraries | OXA1L, SPOUT1, BCAT2 | DPP4 154/4885DPP8 174/4885DPP9 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.