Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734393 | 0.92 | CNR1 (0.50) | GAAL3MBTL1LMNACNR1PKM | |
| SCHEMBL5735877 | 0.90 | MAPT (0.53) | LMNAALDH1A1CNR1PKMSMN1; SMN2 | |
| SCHEMBL5735531 | 0.90 | MAPT (0.53) | L3MBTL1LMNAALDH1A1CNR1PKM | |
| SCHEMBL5735192 | 0.89 | CNR1 (0.50) | GAAL3MBTL1LMNAALDH1A1CNR1 | |
| SCHEMBL5735064 | 0.88 | LSS (0.54) | GAAL3MBTL1LMNAALDH1A1CNR1 | |
| SCHEMBL5737127 | 0.87 | RAB9A (0.52) | ALDH1A1CNR1PKMOXTRATM | |
| SCHEMBL5736717 | 0.87 | CNR1 (0.46) | GAAL3MBTL1LMNAALDH1A1CNR1 | |
| SCHEMBL5733928 | 0.87 | CNR1 (0.46) | GAAL3MBTL1LMNACNR1PKM | |
| SCHEMBL5734332 | 0.87 | SCN9A (0.49) | L3MBTL1LMNACNR1PKMOXTR | |
| SCHEMBL5738054 | 0.87 | GLA (0.48) | LMNAALDH1A1CNR1PKMOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |