Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735374 | 0.85 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL5669623 | 0.85 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL8281816 | 0.85 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL5735085 | 0.83 | BACE1 (0.55) | BACE1CTSD | |
| SCHEMBL8283510 | 0.82 | BACE1 (0.66) | BACE1CTSD | |
| SCHEMBL5669380 | 0.82 | BACE1 (0.66) | BACE1CTSD | |
| SCHEMBL5735885 | 0.79 | BACE1 (0.55) | BACE1CTSD | |
| SCHEMBL6040984 | 0.78 | CTSD (0.57) | BACE1CTSD | |
| SCHEMBL8281522 | 0.78 | CTSD (0.57) | BACE1CTSD | |
| SCHEMBL5667091 | 0.78 | BACE1 (0.71) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734942-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005087215-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |